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Synthetic aminopyrrolic receptors have apoptosis inducing activity

We report two synthetic aminopyrrolic compounds that induce apoptotic cell death. These compounds have been previously shown to act as receptors for mannosides. The extent of receptor-induced cell death is greater in cells expressing a high level of high-mannose oligosaccharides than in cells produc...

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Detalles Bibliográficos
Autores principales: Park, Seong-Hyun, Choi, Yoon Pyo, Park, Jinhong, Share, Andrew, Francesconi, Oscar, Nativi, Cristina, Namkung, Wan, Sessler, Jonathan L., Roelens, Stefano, Shin, Injae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512143/
https://www.ncbi.nlm.nih.gov/pubmed/28757987
http://dx.doi.org/10.1039/c5sc03200h