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Use of mRNA expression signatures to discover small molecule inhibitors of skeletal muscle atrophy

PURPOSE OF REVIEW: Here, we discuss a recently developed experimental strategy for discovering small molecules with potential to prevent and treat skeletal muscle atrophy. RECENT FINDINGS: Muscle atrophy involves and requires widespread changes in skeletal muscle gene expression, which generate comp...

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Detalles Bibliográficos
Autores principales:	Adams, Christopher M., Ebert, Scott M., Dyle, Michael C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512448/ https://www.ncbi.nlm.nih.gov/pubmed/25807353 http://dx.doi.org/10.1097/MCO.0000000000000159

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