Postmortem Findings for 7 Neonates with Congenital Zika Virus Infection

Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pul...

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Detalles Bibliográficos
Autores principales: Sousa, Anastácio Q., Cavalcante, Diane I.M., Franco, Luciano M., Araújo, Fernanda M.C., Sousa, Emília T., Valença-Junior, José Telmo, Rolim, Dionne B., Melo, Maria E.L., Sindeaux, Pedro D.T., Araújo, Marialva T.F., Pearson, Richard D., Wilson, Mary E., Pompeu, Margarida M.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512501/
https://www.ncbi.nlm.nih.gov/pubmed/28459414
http://dx.doi.org/10.3201/eid2307.162019
Descripción
Sumario:Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection.

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