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Microfluidic single-cell transcriptional analysis rationally identifies novel surface marker profiles to enhance cell-based therapies
Current progenitor cell therapies have only modest efficacy, which has limited their clinical adoption. This may be the result of a cellular heterogeneity that decreases the number of functional progenitors delivered to diseased tissue, and prevents correction of underlying pathologic cell populatio...
Autores principales: | Rennert, Robert C., Januszyk, Michael, Sorkin, Michael, Rodrigues, Melanie, Maan, Zeshaan N., Duscher, Dominik, Whittam, Alexander J., Kosaraju, Revanth, Chung, Michael T., Paik, Kevin, Li, Alexander Y., Findlay, Michael, Glotzbach, Jason P., Butte, Atul J., Gurtner, Geoffrey C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512622/ https://www.ncbi.nlm.nih.gov/pubmed/27324848 http://dx.doi.org/10.1038/ncomms11945 |
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