Pyrin-only protein 2 limits inflammation but improves protection against bacteria

Pyrin domain-only proteins (POPs) are recently evolved, primate-specific proteins demonstrated in vitro as negative regulators of inflammatory responses. However, their in vivo function is not understood. Of the four known POPs, only POP2 is reported to regulate NF-κB-dependent transcription and mul...

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Detalles Bibliográficos
Autores principales: Periasamy, Sivakumar, Porter, Kristen A., Atianand, Maninjay K., T. Le, Hongnga, Earley, Sarah, Duffy, Ellen B., Haller, Matthew C., Chin, Heather, Harton, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512670/
https://www.ncbi.nlm.nih.gov/pubmed/28580947
http://dx.doi.org/10.1038/ncomms15564

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