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Thermophoretic migration of vesicles depends on mean temperature and head group chemistry
A number of colloidal systems, including polymers, proteins, micelles and hard spheres, have been studied in thermal gradients to observe and characterize their driven motion. Here we show experimentally the thermophoretic behaviour of unilamellar lipid vesicles, finding that mobility depends on the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512737/ https://www.ncbi.nlm.nih.gov/pubmed/28513597 http://dx.doi.org/10.1038/ncomms15351 |
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author | Talbot, Emma L. Kotar, Jurij Parolini, Lucia Di Michele, Lorenzo Cicuta, Pietro |
author_facet | Talbot, Emma L. Kotar, Jurij Parolini, Lucia Di Michele, Lorenzo Cicuta, Pietro |
author_sort | Talbot, Emma L. |
collection | PubMed |
description | A number of colloidal systems, including polymers, proteins, micelles and hard spheres, have been studied in thermal gradients to observe and characterize their driven motion. Here we show experimentally the thermophoretic behaviour of unilamellar lipid vesicles, finding that mobility depends on the mean local temperature of the suspension and on the structure of the exposed polar lipid head groups. By tuning the temperature, vesicles can be directed towards hot or cold, forming a highly concentrated region. Binary mixtures of vesicles composed of different lipids can be segregated using thermophoresis, according to their head group. Our results demonstrate that thermophoresis enables robust and chemically specific directed motion of liposomes, which can be exploited in driven processes. |
format | Online Article Text |
id | pubmed-5512737 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-55127372017-07-19 Thermophoretic migration of vesicles depends on mean temperature and head group chemistry Talbot, Emma L. Kotar, Jurij Parolini, Lucia Di Michele, Lorenzo Cicuta, Pietro Nat Commun Article A number of colloidal systems, including polymers, proteins, micelles and hard spheres, have been studied in thermal gradients to observe and characterize their driven motion. Here we show experimentally the thermophoretic behaviour of unilamellar lipid vesicles, finding that mobility depends on the mean local temperature of the suspension and on the structure of the exposed polar lipid head groups. By tuning the temperature, vesicles can be directed towards hot or cold, forming a highly concentrated region. Binary mixtures of vesicles composed of different lipids can be segregated using thermophoresis, according to their head group. Our results demonstrate that thermophoresis enables robust and chemically specific directed motion of liposomes, which can be exploited in driven processes. Nature Publishing Group 2017-05-17 /pmc/articles/PMC5512737/ /pubmed/28513597 http://dx.doi.org/10.1038/ncomms15351 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Talbot, Emma L. Kotar, Jurij Parolini, Lucia Di Michele, Lorenzo Cicuta, Pietro Thermophoretic migration of vesicles depends on mean temperature and head group chemistry |
title | Thermophoretic migration of vesicles depends on mean temperature and head group chemistry |
title_full | Thermophoretic migration of vesicles depends on mean temperature and head group chemistry |
title_fullStr | Thermophoretic migration of vesicles depends on mean temperature and head group chemistry |
title_full_unstemmed | Thermophoretic migration of vesicles depends on mean temperature and head group chemistry |
title_short | Thermophoretic migration of vesicles depends on mean temperature and head group chemistry |
title_sort | thermophoretic migration of vesicles depends on mean temperature and head group chemistry |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512737/ https://www.ncbi.nlm.nih.gov/pubmed/28513597 http://dx.doi.org/10.1038/ncomms15351 |
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