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Integrating multi-omics analyses of Nonomuraea dietziae to reveal the role of soybean oil in [(4′-OH)MeLeu](4)-CsA overproduction

BACKGROUND: Nonomuraea dietziae is a promising microorganism to mediate the region-specific monooxygenation reaction of cyclosporine A (CsA). The main product [(4′-OH)MeLeu](4)-CsA possesses high anti-HIV/HCV and hair growth-stimulating activities while avoiding the immunosuppressive effect of CsA....

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Detalles Bibliográficos
Autores principales:	Liu, Huanhuan, Huang, Di, Jin, Lina, Wang, Cheng, Liang, Shaoxiong, Wen, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512743/ https://www.ncbi.nlm.nih.gov/pubmed/28709434 http://dx.doi.org/10.1186/s12934-017-0739-0

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