Improved microRNA suppression by WPRE-linked tough decoy microRNA sponges

Our genes are post-transcriptionally regulated by microRNAs (miRNAs) inducing translational suppression and degradation of targeted mRNAs. Strategies to inhibit miRNAs in a spatiotemporal manner in a desired cell type or tissue, or at a desired developmental stage, can be crucial for understanding m...

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Detalles Bibliográficos
Autores principales: Hollensen, Anne Kruse, Thomsen, Rune, Bak, Rasmus O., Petersen, Charlotte Christie, Ermegaard, Eva R., Aagaard, Lars, Damgaard, Christian Kroun, Mikkelsen, Jacob Giehm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513069/
https://www.ncbi.nlm.nih.gov/pubmed/28487381
http://dx.doi.org/10.1261/rna.061192.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513069/
https://www.ncbi.nlm.nih.gov/pubmed/28487381
http://dx.doi.org/10.1261/rna.061192.117

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