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Study protocol: safety and efficacy of propranolol 0.2% eye drops in newborns with a precocious stage of retinopathy of prematurity (DROP-ROP-0.2%): a multicenter, open-label, single arm, phase II trial
BACKGROUND: Retinopathy of prematurity (ROP) still represents one of the leading causes of visual impairment in childhood. Systemic propranolol has proven to be effective in reducing ROP progression in preterm newborns, although safety was not sufficiently guaranteed. On the contrary, topical treatm...
Autores principales: | Filippi, Luca, Cavallaro, Giacomo, Berti, Elettra, Padrini, Letizia, Araimo, Gabriella, Regiroli, Giulia, Bozzetti, Valentina, De Angelis, Chiara, Tagliabue, Paolo, Tomasini, Barbara, Buonocore, Giuseppe, Agosti, Massimo, Bossi, Angela, Chirico, Gaetano, Aversa, Salvatore, Pasqualetti, Roberta, Fortunato, Pina, Osnaghi, Silvia, Cavallotti, Barbara, Vanni, Maurizio, Borsari, Giulia, Donati, Simone, Nascimbeni, Giuseppe, la Marca, Giancarlo, Forni, Giulia, Milani, Silvano, Cortinovis, Ivan, Bagnoli, Paola, Dal Monte, Massimo, Calvani, Anna Maria, Pugi, Alessandra, Villamor, Eduardo, Donzelli, Gianpaolo, Mosca, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513165/ https://www.ncbi.nlm.nih.gov/pubmed/28709412 http://dx.doi.org/10.1186/s12887-017-0923-8 |
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