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Potassium citrate prevents increased osteoclastogenesis resulting from acidic conditions: Implication for the treatment of postmenopausal bone loss
The extracellular acidic milieu in bones results in activation of osteoclasts (OC) and inhibition of osteoblasts (OB) causing a net loss of calcium from the skeleton and the deterioration of bone microarchitecture. Alkalinization through supplementation with potassium citrate (K citrate) has been pr...
Autores principales: | Granchi, Donatella, Torreggiani, Elena, Massa, Annamaria, Caudarella, Renata, Di Pompo, Gemma, Baldini, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513456/ https://www.ncbi.nlm.nih.gov/pubmed/28715463 http://dx.doi.org/10.1371/journal.pone.0181230 |
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