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Synthetic melanin bound to subunit vaccine antigens significantly enhances CD8(+) T-cell responses

Cytotoxic T-lymphocytes (CTLs) play a key role in immunity against cancer; however, the induction of CTL responses with currently available vaccines remains difficult. Because several reports have suggested that pigmentation and immunity might be functionally linked, we investigated whether melanin...

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Detalles Bibliográficos
Autores principales: Carpentier, Antoine F., Geinguenaud, Frédéric, Tran, Thi, Sejalon, Floraly, Martin, Antoine, Motte, Laurence, Tartour, Eric, Banissi, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513539/
https://www.ncbi.nlm.nih.gov/pubmed/28715455
http://dx.doi.org/10.1371/journal.pone.0181403