Treatment with integrase inhibitor suggests a new interpretation of HIV RNA decay curves that reveals a subset of cells with slow integration

The kinetics of HIV-1 decay under treatment depends on the class of antiretrovirals used. Mathematical models are useful to interpret the different profiles, providing quantitative information about the kinetics of virus replication and the cell populations contributing to viral decay. We modeled pr...

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Detalles Bibliográficos
Autores principales: Cardozo, E. Fabian, Andrade, Adriana, Mellors, John W., Kuritzkes, Daniel R., Perelson, Alan S., Ribeiro, Ruy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513547/
https://www.ncbi.nlm.nih.gov/pubmed/28678879
http://dx.doi.org/10.1371/journal.ppat.1006478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513547/
https://www.ncbi.nlm.nih.gov/pubmed/28678879
http://dx.doi.org/10.1371/journal.ppat.1006478

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