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The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells
Ovarian cancer is the leading cause of death in women with gynecological cancers and despite recent advances, new and more efficient therapies are crucially needed. Müllerian Inhibiting Substance type II Receptor (MISRII, also named AMHRII) is expressed in most ovarian cancer subtypes and is a novel...
Autores principales: | Estupina, Pauline, Fontayne, Alexandre, Barret, Jean-Marc, Kersual, Nathalie, Dubreuil, Olivier, Le Blay, Marion, Pichard, Alexandre, Jarlier, Marta, Pugnière, Martine, Chauvin, Maëva, Chardès, Thierry, Pouget, Jean-Pierre, Deshayes, Emmanuel, Rossignol, Alexis, Abache, Toufik, de Romeuf, Christophe, Terrier, Aurélie, Verhaeghe, Lucie, Gaucher, Christine, Prost, Jean-François, Pèlegrin, André, Navarro-Teulon, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513714/ https://www.ncbi.nlm.nih.gov/pubmed/28427157 http://dx.doi.org/10.18632/oncotarget.15715 |
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