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Human ribosomal P1-P2 heterodimer represents an optimal docking site for ricin A chain with a prominent role for P1 C-terminus
The eukaryotic P-stalk contains two P1-P2 protein dimers with a conserved C- terminal domain (CTD) critical for the interaction with external factors. To understand the role of the individual CTD of human P1/P2 proteins, we examined the interaction of reconstituted human P-protein complexes and C-te...
Autores principales: | Grela, Przemysław, Li, Xiao-Ping, Horbowicz, Patrycja, Dźwierzyńska, Monika, Tchórzewski, Marek, Tumer, Nilgun E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514047/ https://www.ncbi.nlm.nih.gov/pubmed/28717148 http://dx.doi.org/10.1038/s41598-017-05675-5 |
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