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Loss of type 9 adenylyl cyclase triggers reduced phosphorylation of Hsp20 and diastolic dysfunction
Adenylyl cyclase type 9 (AC9) is found tightly associated with the scaffolding protein Yotiao and the I(Ks) ion channel in heart. But apart from potential I(Ks) regulation, physiological roles for AC9 are unknown. We show that loss of AC9 in mice reduces less than 3% of total AC activity in heart bu...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514062/ https://www.ncbi.nlm.nih.gov/pubmed/28717248 http://dx.doi.org/10.1038/s41598-017-05816-w |