Photonic Needles for Light Delivery in Deep Tissue-like Media

We demonstrate a new platform for minimally invasive, light delivery probes leveraging the maturing field of silicon photonics, enabling massively parallel fabrication of photonic structures. These Photonic Needles probes have sub-10 μm cross-sectional dimensions, lengths greater than 3 mm–surpassin...

Descripción completa

Detalles Bibliográficos
Autores principales: Fain, Romy, Barbosa, Felippe, Cardenas, Jaime, Lipson, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514084/
https://www.ncbi.nlm.nih.gov/pubmed/28717142
http://dx.doi.org/10.1038/s41598-017-05746-7
_version_ 1783250775204429824
author Fain, Romy
Barbosa, Felippe
Cardenas, Jaime
Lipson, Michal
author_facet Fain, Romy
Barbosa, Felippe
Cardenas, Jaime
Lipson, Michal
author_sort Fain, Romy
collection PubMed
description We demonstrate a new platform for minimally invasive, light delivery probes leveraging the maturing field of silicon photonics, enabling massively parallel fabrication of photonic structures. These Photonic Needles probes have sub-10 μm cross-sectional dimensions, lengths greater than 3 mm–surpassing 1000 to 1 aspect ratio, and are released completely into air without a substrate below. We show the Photonic Needles to be mechanically robust when inserted into 2% agarose. The propagation loss of these waveguides is low–on the order of 4 dB/cm.
format Online
Article
Text
id pubmed-5514084
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-55140842017-07-19 Photonic Needles for Light Delivery in Deep Tissue-like Media Fain, Romy Barbosa, Felippe Cardenas, Jaime Lipson, Michal Sci Rep Article We demonstrate a new platform for minimally invasive, light delivery probes leveraging the maturing field of silicon photonics, enabling massively parallel fabrication of photonic structures. These Photonic Needles probes have sub-10 μm cross-sectional dimensions, lengths greater than 3 mm–surpassing 1000 to 1 aspect ratio, and are released completely into air without a substrate below. We show the Photonic Needles to be mechanically robust when inserted into 2% agarose. The propagation loss of these waveguides is low–on the order of 4 dB/cm. Nature Publishing Group UK 2017-07-17 /pmc/articles/PMC5514084/ /pubmed/28717142 http://dx.doi.org/10.1038/s41598-017-05746-7 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Fain, Romy
Barbosa, Felippe
Cardenas, Jaime
Lipson, Michal
Photonic Needles for Light Delivery in Deep Tissue-like Media
title Photonic Needles for Light Delivery in Deep Tissue-like Media
title_full Photonic Needles for Light Delivery in Deep Tissue-like Media
title_fullStr Photonic Needles for Light Delivery in Deep Tissue-like Media
title_full_unstemmed Photonic Needles for Light Delivery in Deep Tissue-like Media
title_short Photonic Needles for Light Delivery in Deep Tissue-like Media
title_sort photonic needles for light delivery in deep tissue-like media
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514084/
https://www.ncbi.nlm.nih.gov/pubmed/28717142
http://dx.doi.org/10.1038/s41598-017-05746-7
work_keys_str_mv AT fainromy photonicneedlesforlightdeliveryindeeptissuelikemedia
AT barbosafelippe photonicneedlesforlightdeliveryindeeptissuelikemedia
AT cardenasjaime photonicneedlesforlightdeliveryindeeptissuelikemedia
AT lipsonmichal photonicneedlesforlightdeliveryindeeptissuelikemedia

Ejemplares similares