TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis

The TRAIL pathway can mediate apoptosis of hepatic stellate cells to promote the resolution of liver fibrosis. However, TRAIL has the capacity to bind to regulatory receptors in addition to death-inducing receptors; their differential roles in liver fibrosis have not been investigated. Here we have...

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Detalles Bibliográficos
Autores principales: Singh, Harsimran D., Otano, Itziar, Rombouts, Krista, Singh, Kasha P., Peppa, Dimitra, Gill, Upkar S., Böttcher, Katrin, Kennedy, Patrick T. F., Oben, Jude, Pinzani, Massimo, Walczak, Henning, Fusai, Giuseppe, Rosenberg, William M. C., Maini, Mala K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514093/
https://www.ncbi.nlm.nih.gov/pubmed/28717244
http://dx.doi.org/10.1038/s41598-017-05845-5

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