Targeting Cellular Calcium Homeostasis to Prevent Cytokine-Mediated Beta Cell Death

Pro-inflammatory cytokines are important mediators of islet inflammation, leading to beta cell death in type 1 diabetes. Although alterations in both endoplasmic reticulum (ER) and cytosolic free calcium levels are known to play a role in cytokine-mediated beta cell death, there are currently no tre...

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Detalles Bibliográficos
Autores principales: Clark, Amy L., Kanekura, Kohsuke, Lavagnino, Zeno, Spears, Larry D., Abreu, Damien, Mahadevan, Jana, Yagi, Takuya, Semenkovich, Clay F., Piston, David W., Urano, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514111/
https://www.ncbi.nlm.nih.gov/pubmed/28717166
http://dx.doi.org/10.1038/s41598-017-05935-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514111/
https://www.ncbi.nlm.nih.gov/pubmed/28717166
http://dx.doi.org/10.1038/s41598-017-05935-4

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