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Prostacyclin reverses platelet stress fibre formation causing platelet aggregate instability

Prostacyclin (PGI(2)) modulates platelet activation to regulate haemostasis. Evidence has emerged to suggest that thrombi are dynamic structures with distinct areas of differing platelet activation. It was hypothesised that PGI(2) could reverse platelet spreading by actin cytoskeletal modulation, le...

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Detalles Bibliográficos
Autores principales: Yusuf, M. Z., Raslan, Z., Atkinson, L., Aburima, A., Thomas, S. G., Naseem, K. M., Calaminus, S. D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514131/
https://www.ncbi.nlm.nih.gov/pubmed/28717253
http://dx.doi.org/10.1038/s41598-017-05817-9