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Prostacyclin reverses platelet stress fibre formation causing platelet aggregate instability
Prostacyclin (PGI(2)) modulates platelet activation to regulate haemostasis. Evidence has emerged to suggest that thrombi are dynamic structures with distinct areas of differing platelet activation. It was hypothesised that PGI(2) could reverse platelet spreading by actin cytoskeletal modulation, le...
Autores principales: | Yusuf, M. Z., Raslan, Z., Atkinson, L., Aburima, A., Thomas, S. G., Naseem, K. M., Calaminus, S. D. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514131/ https://www.ncbi.nlm.nih.gov/pubmed/28717253 http://dx.doi.org/10.1038/s41598-017-05817-9 |
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