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TRIB1 is a positive regulator of hepatocyte nuclear factor 4-alpha

The TRIB1 locus has been linked to both cardiovascular disease and hepatic steatosis. Recent efforts have revealed TRIB1 to be a major regulator of liver function, largely, but not exclusively, via CEBPA degradation. We recently uncovered a functional interaction between TRIB1 and HNF4A, another key...

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Detalles Bibliográficos
Autores principales:	Soubeyrand, Sébastien, Martinuk, Amy, McPherson, Ruth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514136/ https://www.ncbi.nlm.nih.gov/pubmed/28717196 http://dx.doi.org/10.1038/s41598-017-05768-1

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