Cargando…

Self versus informant reports on the specific levels of functioning scale: Relationships to depression and cognition in schizophrenia and schizoaffective disorder

The goal of the current study was to examine the relationships between insight and both cognitive function and depression in schizophrenia and schizoaffective disorder, and to determine if there were similar relationships across diagnostic categories. We examined discrepancies between self and infor...

Descripción completa

Detalles Bibliográficos
Autores principales: Ermel, Julia, Carter, Cameron S., Gold, James M., MacDonald, Angus W., Daniel Ragland, J., Silverstein, Steven M., Strauss, Milton E., Barch, Deanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514389/
https://www.ncbi.nlm.nih.gov/pubmed/28740827
http://dx.doi.org/10.1016/j.scog.2017.04.001
_version_ 1783250831567486976
author Ermel, Julia
Carter, Cameron S.
Gold, James M.
MacDonald, Angus W.
Daniel Ragland, J.
Silverstein, Steven M.
Strauss, Milton E.
Barch, Deanna M.
author_facet Ermel, Julia
Carter, Cameron S.
Gold, James M.
MacDonald, Angus W.
Daniel Ragland, J.
Silverstein, Steven M.
Strauss, Milton E.
Barch, Deanna M.
author_sort Ermel, Julia
collection PubMed
description The goal of the current study was to examine the relationships between insight and both cognitive function and depression in schizophrenia and schizoaffective disorder, and to determine if there were similar relationships across diagnostic categories. We examined discrepancies between self and informant reports of function on the Specific levels of function scale as a metric of insight for interpersonal, social acceptance, work and activities. We examined two samples of individuals with schizophrenia and/or schizoaffective disorder (Ns of 188 and 67 respectively). In Sample 1, cognition was measured using the Dot Probe Expectancy Task. In Sample 2, cognition was measured by averaging several subtests from the MATRICS consensus cognitive battery, as well as additional measures of working memory. In both samples, depression was measured using the Brief Psychiatric Rating Scale. In both samples, we found significant relationships between worse cognition and overestimations of work function, as well as between higher depression levels and underestimation of interpersonal function. These relationships were specific to interpersonal and work function, with significantly stronger correlations with interpersonal and work function compared to the other areas of function. Similar results were found across diagnostic categories. These results have important implications for treatment planning, as they suggest the need to take into account depression and cognitive function when evaluating the patient's self-report of function, and highlight the utility of informant reports in evaluating function and treatment planning. Further, they add to the literature on the similarity across schizophrenia and schizoaffective disorder in a variety of pathological mechanisms.
format Online
Article
Text
id pubmed-5514389
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-55143892017-07-24 Self versus informant reports on the specific levels of functioning scale: Relationships to depression and cognition in schizophrenia and schizoaffective disorder Ermel, Julia Carter, Cameron S. Gold, James M. MacDonald, Angus W. Daniel Ragland, J. Silverstein, Steven M. Strauss, Milton E. Barch, Deanna M. Schizophr Res Cogn Research Paper The goal of the current study was to examine the relationships between insight and both cognitive function and depression in schizophrenia and schizoaffective disorder, and to determine if there were similar relationships across diagnostic categories. We examined discrepancies between self and informant reports of function on the Specific levels of function scale as a metric of insight for interpersonal, social acceptance, work and activities. We examined two samples of individuals with schizophrenia and/or schizoaffective disorder (Ns of 188 and 67 respectively). In Sample 1, cognition was measured using the Dot Probe Expectancy Task. In Sample 2, cognition was measured by averaging several subtests from the MATRICS consensus cognitive battery, as well as additional measures of working memory. In both samples, depression was measured using the Brief Psychiatric Rating Scale. In both samples, we found significant relationships between worse cognition and overestimations of work function, as well as between higher depression levels and underestimation of interpersonal function. These relationships were specific to interpersonal and work function, with significantly stronger correlations with interpersonal and work function compared to the other areas of function. Similar results were found across diagnostic categories. These results have important implications for treatment planning, as they suggest the need to take into account depression and cognitive function when evaluating the patient's self-report of function, and highlight the utility of informant reports in evaluating function and treatment planning. Further, they add to the literature on the similarity across schizophrenia and schizoaffective disorder in a variety of pathological mechanisms. Elsevier 2017-05-09 /pmc/articles/PMC5514389/ /pubmed/28740827 http://dx.doi.org/10.1016/j.scog.2017.04.001 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Paper
Ermel, Julia
Carter, Cameron S.
Gold, James M.
MacDonald, Angus W.
Daniel Ragland, J.
Silverstein, Steven M.
Strauss, Milton E.
Barch, Deanna M.
Self versus informant reports on the specific levels of functioning scale: Relationships to depression and cognition in schizophrenia and schizoaffective disorder
title Self versus informant reports on the specific levels of functioning scale: Relationships to depression and cognition in schizophrenia and schizoaffective disorder
title_full Self versus informant reports on the specific levels of functioning scale: Relationships to depression and cognition in schizophrenia and schizoaffective disorder
title_fullStr Self versus informant reports on the specific levels of functioning scale: Relationships to depression and cognition in schizophrenia and schizoaffective disorder
title_full_unstemmed Self versus informant reports on the specific levels of functioning scale: Relationships to depression and cognition in schizophrenia and schizoaffective disorder
title_short Self versus informant reports on the specific levels of functioning scale: Relationships to depression and cognition in schizophrenia and schizoaffective disorder
title_sort self versus informant reports on the specific levels of functioning scale: relationships to depression and cognition in schizophrenia and schizoaffective disorder
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514389/
https://www.ncbi.nlm.nih.gov/pubmed/28740827
http://dx.doi.org/10.1016/j.scog.2017.04.001
work_keys_str_mv AT ermeljulia selfversusinformantreportsonthespecificlevelsoffunctioningscalerelationshipstodepressionandcognitioninschizophreniaandschizoaffectivedisorder
AT cartercamerons selfversusinformantreportsonthespecificlevelsoffunctioningscalerelationshipstodepressionandcognitioninschizophreniaandschizoaffectivedisorder
AT goldjamesm selfversusinformantreportsonthespecificlevelsoffunctioningscalerelationshipstodepressionandcognitioninschizophreniaandschizoaffectivedisorder
AT macdonaldangusw selfversusinformantreportsonthespecificlevelsoffunctioningscalerelationshipstodepressionandcognitioninschizophreniaandschizoaffectivedisorder
AT danielraglandj selfversusinformantreportsonthespecificlevelsoffunctioningscalerelationshipstodepressionandcognitioninschizophreniaandschizoaffectivedisorder
AT silversteinstevenm selfversusinformantreportsonthespecificlevelsoffunctioningscalerelationshipstodepressionandcognitioninschizophreniaandschizoaffectivedisorder
AT straussmiltone selfversusinformantreportsonthespecificlevelsoffunctioningscalerelationshipstodepressionandcognitioninschizophreniaandschizoaffectivedisorder
AT barchdeannam selfversusinformantreportsonthespecificlevelsoffunctioningscalerelationshipstodepressionandcognitioninschizophreniaandschizoaffectivedisorder