Multiplex Ultrasensitive Genotyping of Patients with Non-Small Cell Lung Cancer for Epidermal Growth Factor Receptor (EGFR) Mutations by Means of Picodroplet Digital PCR

Epidermal growth factor receptor (EGFR) mutations have been used as the strongest predictor of effectiveness of treatment with EGFR tyrosine kinase inhibitors (TKIs). Three most common EGFR mutations (L858R, exon 19 deletion, and T790M) are known to be major selection markers for EGFR-TKIs therapy....

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Detalles Bibliográficos
Autores principales: Watanabe, Masaru, Kawaguchi, Tomoya, Isa, Shun-ichi, Ando, Masahiko, Tamiya, Akihiro, Kubo, Akihito, Saka, Hideo, Takeo, Sadanori, Adachi, Hirofumi, Tagawa, Tsutomu, Kawashima, Osamu, Yamashita, Motohiro, Kataoka, Kazuhiko, Ichinose, Yukito, Takeuchi, Yukiyasu, Watanabe, Katsuya, Matsumura, Akihide, Koh, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514407/
https://www.ncbi.nlm.nih.gov/pubmed/28625519
http://dx.doi.org/10.1016/j.ebiom.2017.06.003

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