NKCC1 Regulates Migration Ability of Glioblastoma Cells by Modulation of Actin Dynamics and Interacting with Cofilin

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults. The mechanisms that confer GBM cells their invasive behavior are poorly understood. The electroneutral Na(+)-K(+)-2Cl(−) co-transporter 1 (NKCC1) is an important cell volume regulator that participates in cell migration. We hav...

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Detalles Bibliográficos
Autores principales: Schiapparelli, Paula, Guerrero-Cazares, Hugo, Magaña-Maldonado, Roxana, Hamilla, Susan M., Ganaha, Sara, Goulin Lippi Fernandes, Eric, Huang, Chuan-Hsiang, Aranda-Espinoza, Helim, Devreotes, Peter, Quinones-Hinojosa, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514434/
https://www.ncbi.nlm.nih.gov/pubmed/28679472
http://dx.doi.org/10.1016/j.ebiom.2017.06.020

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