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Progressive hypoventilation due to mixed CD8(+) and CD4(+) lymphocytic polymyositis following tremelimumab - durvalumab treatment

BACKGROUND: The combination of CTLA-4 and PD-L1 inhibitors has a manageable adverse effect profile, although rare immune-related adverse events (irAE) can occur. CASE PRESENTATION: We describe an autoimmune polymyositis following a partial response to combination tremelimumab and durvalumab for the...

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Detalles Bibliográficos
Autores principales:	John, Sooraj, Antonia, Scott J., Rose, Trevor A., Seifert, Robert P., Centeno, Barbara A., Wagner, Aaron S., Creelan, Ben C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514517/ https://www.ncbi.nlm.nih.gov/pubmed/28716137 http://dx.doi.org/10.1186/s40425-017-0258-x

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