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An efficient algorithm for improving structure-based prediction of transcription factor binding sites

BACKGROUND: Gene expression is regulated by transcription factors binding to specific target DNA sites. Understanding how and where transcription factors bind at genome scale represents an essential step toward our understanding of gene regulation networks. Previously we developed a structure-based...

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Detalles Bibliográficos
Autores principales: Farrel, Alvin, Guo, Jun-tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514533/
https://www.ncbi.nlm.nih.gov/pubmed/28715997
http://dx.doi.org/10.1186/s12859-017-1755-0