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Cutaneous mucormycosis

Cutaneous mucormycosis is an emerging fungal infection caused by opportunistic fungi of the phylum Glomeromycota. It is frequent in poorly controlled diabetic patients and individuals with immunosuppression. It is usually acquired by direct inoculation through trauma. The clinical presentation is no...

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Autores principales: Castrejón-Pérez, Ana Daniela, Welsh, Esperanza C., Miranda, Ivett, Ocampo-Candiani, Jorge, Welsh, Oliverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514567/
https://www.ncbi.nlm.nih.gov/pubmed/29186239
http://dx.doi.org/10.1590/abd1806-4841.20176614
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author Castrejón-Pérez, Ana Daniela
Welsh, Esperanza C.
Miranda, Ivett
Ocampo-Candiani, Jorge
Welsh, Oliverio
author_facet Castrejón-Pérez, Ana Daniela
Welsh, Esperanza C.
Miranda, Ivett
Ocampo-Candiani, Jorge
Welsh, Oliverio
author_sort Castrejón-Pérez, Ana Daniela
collection PubMed
description Cutaneous mucormycosis is an emerging fungal infection caused by opportunistic fungi of the phylum Glomeromycota. It is frequent in poorly controlled diabetic patients and individuals with immunosuppression. It is usually acquired by direct inoculation through trauma. The clinical presentation is nonspecific, but an indurated plaque that rapidly evolves to necrosis is a common finding. Diagnosis should be confirmed by demonstration of the etiological agent and new molecular diagnostic tools have recently been described. It is an invasive life-threatening disease and in order to improve survival, a prompt diagnosis and multidisciplinary management should be provided. The treatment of choice is amphotericin B, but new azoles, such as posaconazole and isavuconazole, must be considered.
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spelling pubmed-55145672017-07-24 Cutaneous mucormycosis Castrejón-Pérez, Ana Daniela Welsh, Esperanza C. Miranda, Ivett Ocampo-Candiani, Jorge Welsh, Oliverio An Bras Dermatol Continuing Medical Education Cutaneous mucormycosis is an emerging fungal infection caused by opportunistic fungi of the phylum Glomeromycota. It is frequent in poorly controlled diabetic patients and individuals with immunosuppression. It is usually acquired by direct inoculation through trauma. The clinical presentation is nonspecific, but an indurated plaque that rapidly evolves to necrosis is a common finding. Diagnosis should be confirmed by demonstration of the etiological agent and new molecular diagnostic tools have recently been described. It is an invasive life-threatening disease and in order to improve survival, a prompt diagnosis and multidisciplinary management should be provided. The treatment of choice is amphotericin B, but new azoles, such as posaconazole and isavuconazole, must be considered. Sociedade Brasileira de Dermatologia 2017 /pmc/articles/PMC5514567/ /pubmed/29186239 http://dx.doi.org/10.1590/abd1806-4841.20176614 Text en ©2017 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited.
spellingShingle Continuing Medical Education
Castrejón-Pérez, Ana Daniela
Welsh, Esperanza C.
Miranda, Ivett
Ocampo-Candiani, Jorge
Welsh, Oliverio
Cutaneous mucormycosis
title Cutaneous mucormycosis
title_full Cutaneous mucormycosis
title_fullStr Cutaneous mucormycosis
title_full_unstemmed Cutaneous mucormycosis
title_short Cutaneous mucormycosis
title_sort cutaneous mucormycosis
topic Continuing Medical Education
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514567/
https://www.ncbi.nlm.nih.gov/pubmed/29186239
http://dx.doi.org/10.1590/abd1806-4841.20176614
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