Cargando…

Human DMBT1-Derived Cell-Penetrating Peptides for Intracellular siRNA Delivery

Small interfering RNA (siRNA) is a promising molecule for gene therapy, but its therapeutic administration remains problematic. Among the recently proposed vectors, cell-penetrating peptides show great promise in in vivo trials for siRNA delivery. Human protein DMBT1 (deleted in malignant brain tumo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tuttolomondo, Martina, Casella, Cinzia, Hansen, Pernille Lund, Polo, Ester, Herda, Luciana M., Dawson, Kenneth A., Ditzel, Henrik J., Mollenhauer, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514624/ https://www.ncbi.nlm.nih.gov/pubmed/28918028 http://dx.doi.org/10.1016/j.omtn.2017.06.020

Ejemplares similares

Versatility of cell-penetrating peptides for intracellular delivery of siRNA
por: Singh, Tejinder, et al.
Publicado: (2018)

DMBT1 expression is down-regulated in breast cancer
por: Braidotti, P, et al.
Publicado: (2004)

The scavenging capacity of DMBT1 is impaired by germline deletions
por: Bikker, Floris J., et al.
Publicado: (2017)

Dmbt1 does not affect a Western style diet-induced liver damage in mice
por: Reichold, Astrid, et al.
Publicado: (2013)

High DMBT1 concentrations in breast milk correlate with increased risk of infection in preterm and term neonates
por: Ronellenfitsch, Sebastian, et al.
Publicado: (2012)

Albumin pre-coating enhances intracellular siRNA delivery of multifunctional amphiphile/siRNA nanoparticles
por: Kummitha, China M, et al.
Publicado: (2012)

Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles
por: Castillo, Betzaida, et al.
Publicado: (2012)

In situ characterization of nanoparticle biomolecular interactions in complex biological media by flow cytometry
por: Lo Giudice, Maria Cristina, et al.
Publicado: (2016)

Peptide-Ligand Binding Modeling of siRNA with Cell-Penetrating Peptides
por: García-Sosa, Alfonso T., et al.
Publicado: (2014)

A retro-inverso cell-penetrating peptide for siRNA delivery
por: Vaissière, Anaïs, et al.
Publicado: (2017)

Live cell imaging of duplex siRNA intracellular trafficking
por: Hirsch, Markus, et al.
Publicado: (2015)

Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant
por: Müller, Hanna, et al.
Publicado: (2007)

Blood-brain barrier–penetrating siRNA nanomedicine for Alzheimer’s disease therapy
por: Zhou, Yutong, et al.
Publicado: (2020)

Deleted in malignant brain tumors 1 (DMBT1) elicits increased VEGF and decreased IL-6 production in type II lung epithelial cells
por: Müller, Hanna, et al.
Publicado: (2015)

Uptake and intracellular traffic of siRNA dendriplexes in glioblastoma cells and macrophages
por: Perez, Ana Paula, et al.
Publicado: (2011)

Development of siRNA lipoplexes for intracellular delivery in lung cancer cells
por: Khatri, N., et al.
Publicado: (2012)

Modular and hierarchical self-assembly of siRNAs into supramolecular nanomaterials for soft and homogeneous siRNA loading and precise and visualized intracellular delivery
por: Guan, Xiaowen, et al.
Publicado: (2022)

Lack of DMBT1 expression in oesophageal, gastric and colon cancers
por: Mori, M, et al.
Publicado: (1999)

Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas
por: Ren, Yin, et al.
Publicado: (2017)

Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Docking Study
por: Rathnayake, P. V. G. M., et al.
Publicado: (2017)

Cytoplasmic delivery of siRNA using human-derived membrane penetration-enhancing peptide
por: Nakamura, Momoko, et al.
Publicado: (2022)

Development and characterization of chitosan-PEG-TAT nanoparticles for the intracellular delivery of siRNA
por: Malhotra, Meenakshi, et al.
Publicado: (2013)

Integration of Polylactide into Polyethylenimine Facilitates the Safe and Effective Intracellular siRNA Delivery
por: Ding, Guo-Bin, et al.
Publicado: (2020)

Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles
por: Ballarín-González, Borja, et al.
Publicado: (2013)

Expression of the DMBT1 Gene Is Frequently Suppressed in Human Lung Cancer
por: Takeshita, Hiroaki, et al.
Publicado: (1999)

Significance of DMBT1 in Papillary Thyroid Carcinoma Concurrent With Hashimoto’s Thyroiditis
por: Gan, Xiao-xiong, et al.
Publicado: (2021)

siRNA suppression of hTERT using activatable cell-penetrating peptides in hepatoma cells
por: Li, Hua, et al.
Publicado: (2015)

Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions
por: Ezzat, Kariem, et al.
Publicado: (2012)

Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models
por: Kiisholts, Kristina, et al.
Publicado: (2021)

Oleyl Conjugated Histidine-Arginine Cell-Penetrating Peptides as Promising Agents for siRNA Delivery
por: Sajid, Muhammad Imran, et al.
Publicado: (2022)

Regulating intracellular fate of siRNA by endoplasmic reticulum membrane-decorated hybrid nanoplexes
por: Qiu, Chong, et al.
Publicado: (2019)

Deleted in malignant brain tumor 1 genetic variation confers urinary tract infection risk in children and mice
por: Hains, David S., et al.
Publicado: (2021)

Analysis of copy number variation at DMBT1 and age-related macular degeneration
por: Polley, Shamik, et al.
Publicado: (2016)

Expression of PDK-1 and DMBT1 in the thyroid carcinoma and its clinicopathological significance
por: Sun, Zhichao, et al.
Publicado: (2019)

DMBT1 is upregulated in cystic fibrosis, affects ciliary motility, and is reduced by acetylcysteine
por: Kiefer, Alexander, et al.
Publicado: (2022)

Evaluation of CSTB and DMBT1 expression in saliva of gastric cancer patients and controls
por: Koopaie, Maryam, et al.
Publicado: (2022)

Enzyme-triggered PEGylated siRNA-nanoparticles for controlled release of siRNA
por: Yingyuad, Peerada, et al.
Publicado: (2014)

Thermal Stability of siRNA Modulates Aptamer- conjugated siRNA Inhibition
por: Berezhnoy, Alexey, et al.
Publicado: (2012)

Where should siRNAs go: applicable organs for siRNA drugs
por: Ahn, Insook, et al.
Publicado: (2023)

Construction of histidine-containing hydrocarbon stapled cell penetrating peptides for in vitro and in vivo delivery of siRNAs
por: Hyun, Soonsil, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_18rl9olo3eled7n3ubhbk8a2hk