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Genetically Engineered Multilineage-Differentiating Stress-Enduring Cells as Cellular Vehicles against Malignant Gliomas

Malignant glioma, the most common malignant brain tumor in adults, is difficult to treat due to its aggressive invasive nature. Enzyme/prodrug suicide gene therapy based on the herpes simplex virus thymidine kinase (HSVtk)/ganciclovir (GCV) system is an efficient strategy for treating malignant glio...

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Detalles Bibliográficos
Autores principales: Yamasaki, Tomohiro, Wakao, Shohei, Kawaji, Hiroshi, Koizumi, Shinichiro, Sameshima, Tetsuro, Dezawa, Mari, Namba, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514691/
https://www.ncbi.nlm.nih.gov/pubmed/28748212
http://dx.doi.org/10.1016/j.omto.2017.06.001

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