Cargando…

Dietary hemoglobin rescues young piglets from severe iron deficiency anemia: Duodenal expression profile of genes involved in heme iron absorption

Heme is an efficient source of iron in the diet, and heme preparations are used to prevent and cure iron deficiency anemia in humans and animals. However, the molecular mechanisms responsible for heme absorption remain only partially characterized. Here, we employed young iron-deficient piglets as a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Staroń, Robert, Lipiński, Paweł, Lenartowicz, Małgorzata, Bednarz, Aleksandra, Gajowiak, Anna, Smuda, Ewa, Krzeptowski, Wojciech, Pieszka, Marek, Korolonek, Tamara, Hamza, Iqbal, Swinkels, Dorine W., Van Swelm, Rachel P. L., Starzyński, Rafał R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514692/ https://www.ncbi.nlm.nih.gov/pubmed/28704474 http://dx.doi.org/10.1371/journal.pone.0181117

Ejemplares similares

Urinary Hepcidin Levels in Iron-Deficient and Iron-Supplemented Piglets Correlate with Hepcidin Hepatic mRNA and Serum Levels and with Body Iron Status
por: Staroń, Robert, et al.
Publicado: (2015)

Haemolysis and Perturbations in the Systemic Iron Metabolism of Suckling, Copper-Deficient Mosaic Mutant Mice – An Animal Model of Menkes Disease
por: Lenartowicz, Małgorzata, et al.
Publicado: (2014)

Effect of Oral Supplementation of Healthy Pregnant Sows with Sucrosomial Ferric Pyrophosphate on Maternal Iron Status and Hepatic Iron Stores in Newborn Piglets
por: Mazgaj, Rafał, et al.
Publicado: (2020)

Mice Overexpressing Both Non-Mutated Human SOD1 and Mutated SOD1(G93A) Genes: A Competent Experimental Model for Studying Iron Metabolism in Amyotrophic Lateral Sclerosis
por: Gajowiak, Anna, et al.
Publicado: (2016)

Iron Supplementation in Suckling Piglets: How to Correct Iron Deficiency Anemia without Affecting Plasma Hepcidin Levels
por: Starzyński, Rafał R., et al.
Publicado: (2013)

Marginally reduced maternal hepatic and splenic ferroportin under severe nutritional iron deficiency in pregnancy maintains systemic iron supply
por: Mazgaj, Rafał, et al.
Publicado: (2021)

Long-term Effect of Split Iron Dextran/Hemoglobin Supplementation on Erythrocyte and Iron Status, Growth Performance, Carcass Parameters, and Meat Quality of Polish Large White and 990 Line Pigs
por: Szudzik, Mateusz, et al.
Publicado: (2019)

Comparative Evaluation of Sucrosomial Iron and Iron Oxide Nanoparticles as Oral Supplements in Iron Deficiency Anemia in Piglets
por: Mazgaj, Rafał, et al.
Publicado: (2021)

Role of the kidneys in the redistribution of heme-derived iron during neonatal hemolysis in mice
por: Bednarz, Aleksandra, et al.
Publicado: (2019)

Iron Supplementation in Suckling Piglets: An Ostensibly Easy Therapy of Neonatal Iron Deficiency Anemia
por: Szudzik, Mateusz, et al.
Publicado: (2018)

Correction: Mateusz, S., et al. Iron Supplementation in Suckling Piglets: An Ostensibly Easy Therapy of Neonatal Iron Deficiency Anemia. Pharmaceuticals 2018, 11, 128
por: Szudzik, Mateusz, et al.
Publicado: (2019)

Exacerbation of Neonatal Hemolysis and Impaired Renal Iron Handling in Heme Oxygenase 1-Deficient Mice
por: Bednarz, Aleksandra, et al.
Publicado: (2020)

Relationship between Down-Regulation of Copper-Related Genes and Decreased Ferroportin Protein Level in the Duodenum of Iron-Deficient Piglets
por: Jończy, Aneta, et al.
Publicado: (2020)

Differentiating iron-loading anemias using a newly developed and analytically validated ELISA for human serum erythroferrone
por: Diepeveen, Laura, et al.
Publicado: (2021)

Mottled Mice and Non-Mammalian Models of Menkes Disease
por: Lenartowicz, Małgorzata, et al.
Publicado: (2015)

Endogenous hepcidin synthesis protects the distal nephron against hemin and hemoglobin mediated necroptosis
por: van Swelm, Rachel P. L., et al.
Publicado: (2018)

Like iron in the blood of the people: the requirement for heme trafficking in iron metabolism
por: Korolnek, Tamara, et al.
Publicado: (2014)

Tubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease
por: van Raaij, Sanne, et al.
Publicado: (2018)

Bioavailability of Heme Iron in Biscuit Filling Using Piglets as an Animal Model for Humans
por: Quintero-Gutiérrez, Adrián Guillermo, et al.
Publicado: (2008)

Publisher Correction: Tubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease
por: van Raaij, Sanne, et al.
Publicado: (2018)

Unique Heme-Iron Coordination by the Hemoglobin Receptor IsdB of Staphylococcus aureus
por: Gaudin, Catherine F. M., et al.
Publicado: (2011)

Molecular Regulation of Copper Homeostasis in the Male Gonad during the Process of Spermatogenesis
por: Herman, Sylwia, et al.
Publicado: (2020)

Kidney tubule iron loading in experimental focal segmental glomerulosclerosis
por: van Swelm, Rachel P. L., et al.
Publicado: (2022)

HEME AND TISSUE IRON
por: Anson, M. L., et al.
Publicado: (1929)

Emerging Regulatory Role of Nrf2 in Iron, Heme, and Hemoglobin Metabolism in Physiology and Disease
por: Kasai, Shuya, et al.
Publicado: (2018)

Hepcidin suppression and defective iron recycling account for dysregulation of iron homeostasis in heme oxygenase-1 deficiency
por: Kartikasari, Apriliana E R, et al.
Publicado: (2010)

Hepcidin suppression and defective iron recycling account for dysregulation of iron homeostasis in heme oxygenase-1 deficiency
por: Kartikasari, Apriliana E R, et al.
Publicado: (2009)

Molecular insights into the regulation of iron metabolism during the prenatal and early postnatal periods
por: Lipiński, Paweł, et al.
Publicado: (2012)

Iron uptake by ZIP8 and ZIP14 in human proximal tubular epithelial cells
por: van Raaij, S. E. G., et al.
Publicado: (2019)

Heme: The Lord of the Iron Ring
por: Voltarelli, Vanessa Azevedo, et al.
Publicado: (2023)

NEAr Transporter (NEAT) Domains: Unique Surface Displayed Heme Chaperones That Enable Gram-Positive Bacteria to Capture Heme-Iron From Hemoglobin
por: Ellis-Guardiola, Ken, et al.
Publicado: (2021)

Iron Metabolism in the Disorders of Heme Biosynthesis
por: Ricci, Andrea, et al.
Publicado: (2022)

Anisotropic Iron Motion in Nitrosyl Iron Porphyrinates: Natural and Synthetic Hemes
por: Pavlik, Jeffrey W., et al.
Publicado: (2014)

Heme-bound iron in treatment of pregnancy-associated iron deficiency anemia
por: Abdelazim, Ibrahim A., et al.
Publicado: (2018)

Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury
por: Diepeveen, Laura E., et al.
Publicado: (2022)

A Relay Network of Extracellular Heme-Binding Proteins Drives C. albicans Iron Acquisition from Hemoglobin
por: Kuznets, Galit, et al.
Publicado: (2014)

Chloroquine Interference with Hemoglobin Endocytic Trafficking Suppresses Adaptive Heme and Iron Homeostasis in Macrophages: The Paradox of an Antimalarial Agent
por: Schaer, Christian A., et al.
Publicado: (2013)

Normal Iron Homeostasis Requires the Transporter SLC48A1 for Efficient Heme-Iron Recycling in Mammals
por: Simmons, William R., et al.
Publicado: (2020)

Pharmacokinetics of Ferric Pyrophosphate Citrate, a Novel Iron Salt, Administered Intravenously to Healthy Volunteers
por: Pratt, Raymond D., et al.
Publicado: (2016)

Role of Iron Metabolism-Related Genes in Prenatal Development: Insights from Mouse Transgenic Models
por: Kopeć, Zuzanna, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ue12fi362gqh16m4201dgp49vc