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Curcuma longa L. extract improves the cortical neural connectivity during the aging process
Turmeric or Curcuma is a natural product that has anti-inflammatory, antioxidant and anti-apoptotic pharmacological properties. It can be used in the control of the aging process that involves oxidative stress, inflammation, and apoptosis. Aging is a physiological process that affects higher cortica...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514855/ https://www.ncbi.nlm.nih.gov/pubmed/28761413 http://dx.doi.org/10.4103/1673-5374.208542 |
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author | Flores, Gonzalo |
author_facet | Flores, Gonzalo |
author_sort | Flores, Gonzalo |
collection | PubMed |
description | Turmeric or Curcuma is a natural product that has anti-inflammatory, antioxidant and anti-apoptotic pharmacological properties. It can be used in the control of the aging process that involves oxidative stress, inflammation, and apoptosis. Aging is a physiological process that affects higher cortical and cognitive functions with a reduction in learning and memory, limited judgment and deficits in emotional control and social behavior. Moreover, aging is a major risk factor for the appearance of several disorders such as cerebrovascular disease, diabetes mellitus, and hypertension. At the brain level, the aging process alters the synaptic intercommunication by a reduction in the dendritic arbor as well as the number of the dendritic spine in the pyramidal neurons of the prefrontal cortex, hippocampus and basolateral amygdala, consequently reducing the size of these regions. The present review discusses the synaptic changes caused by the aging process and the neuroprotective role the Curcuma has through its anti-inflammatory, antioxidant and anti-apoptotic actions |
format | Online Article Text |
id | pubmed-5514855 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-55148552017-07-31 Curcuma longa L. extract improves the cortical neural connectivity during the aging process Flores, Gonzalo Neural Regen Res Invited Review Turmeric or Curcuma is a natural product that has anti-inflammatory, antioxidant and anti-apoptotic pharmacological properties. It can be used in the control of the aging process that involves oxidative stress, inflammation, and apoptosis. Aging is a physiological process that affects higher cortical and cognitive functions with a reduction in learning and memory, limited judgment and deficits in emotional control and social behavior. Moreover, aging is a major risk factor for the appearance of several disorders such as cerebrovascular disease, diabetes mellitus, and hypertension. At the brain level, the aging process alters the synaptic intercommunication by a reduction in the dendritic arbor as well as the number of the dendritic spine in the pyramidal neurons of the prefrontal cortex, hippocampus and basolateral amygdala, consequently reducing the size of these regions. The present review discusses the synaptic changes caused by the aging process and the neuroprotective role the Curcuma has through its anti-inflammatory, antioxidant and anti-apoptotic actions Medknow Publications & Media Pvt Ltd 2017-06 /pmc/articles/PMC5514855/ /pubmed/28761413 http://dx.doi.org/10.4103/1673-5374.208542 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Invited Review Flores, Gonzalo Curcuma longa L. extract improves the cortical neural connectivity during the aging process |
title | Curcuma longa L. extract improves the cortical neural connectivity during the aging process |
title_full | Curcuma longa L. extract improves the cortical neural connectivity during the aging process |
title_fullStr | Curcuma longa L. extract improves the cortical neural connectivity during the aging process |
title_full_unstemmed | Curcuma longa L. extract improves the cortical neural connectivity during the aging process |
title_short | Curcuma longa L. extract improves the cortical neural connectivity during the aging process |
title_sort | curcuma longa l. extract improves the cortical neural connectivity during the aging process |
topic | Invited Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514855/ https://www.ncbi.nlm.nih.gov/pubmed/28761413 http://dx.doi.org/10.4103/1673-5374.208542 |
work_keys_str_mv | AT floresgonzalo curcumalongalextractimprovesthecorticalneuralconnectivityduringtheagingprocess |