Cargando…

Curcuma longa L. extract improves the cortical neural connectivity during the aging process

Turmeric or Curcuma is a natural product that has anti-inflammatory, antioxidant and anti-apoptotic pharmacological properties. It can be used in the control of the aging process that involves oxidative stress, inflammation, and apoptosis. Aging is a physiological process that affects higher cortica...

Descripción completa

Detalles Bibliográficos
Autor principal: Flores, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514855/
https://www.ncbi.nlm.nih.gov/pubmed/28761413
http://dx.doi.org/10.4103/1673-5374.208542
_version_ 1783250894943420416
author Flores, Gonzalo
author_facet Flores, Gonzalo
author_sort Flores, Gonzalo
collection PubMed
description Turmeric or Curcuma is a natural product that has anti-inflammatory, antioxidant and anti-apoptotic pharmacological properties. It can be used in the control of the aging process that involves oxidative stress, inflammation, and apoptosis. Aging is a physiological process that affects higher cortical and cognitive functions with a reduction in learning and memory, limited judgment and deficits in emotional control and social behavior. Moreover, aging is a major risk factor for the appearance of several disorders such as cerebrovascular disease, diabetes mellitus, and hypertension. At the brain level, the aging process alters the synaptic intercommunication by a reduction in the dendritic arbor as well as the number of the dendritic spine in the pyramidal neurons of the prefrontal cortex, hippocampus and basolateral amygdala, consequently reducing the size of these regions. The present review discusses the synaptic changes caused by the aging process and the neuroprotective role the Curcuma has through its anti-inflammatory, antioxidant and anti-apoptotic actions
format Online
Article
Text
id pubmed-5514855
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-55148552017-07-31 Curcuma longa L. extract improves the cortical neural connectivity during the aging process Flores, Gonzalo Neural Regen Res Invited Review Turmeric or Curcuma is a natural product that has anti-inflammatory, antioxidant and anti-apoptotic pharmacological properties. It can be used in the control of the aging process that involves oxidative stress, inflammation, and apoptosis. Aging is a physiological process that affects higher cortical and cognitive functions with a reduction in learning and memory, limited judgment and deficits in emotional control and social behavior. Moreover, aging is a major risk factor for the appearance of several disorders such as cerebrovascular disease, diabetes mellitus, and hypertension. At the brain level, the aging process alters the synaptic intercommunication by a reduction in the dendritic arbor as well as the number of the dendritic spine in the pyramidal neurons of the prefrontal cortex, hippocampus and basolateral amygdala, consequently reducing the size of these regions. The present review discusses the synaptic changes caused by the aging process and the neuroprotective role the Curcuma has through its anti-inflammatory, antioxidant and anti-apoptotic actions Medknow Publications & Media Pvt Ltd 2017-06 /pmc/articles/PMC5514855/ /pubmed/28761413 http://dx.doi.org/10.4103/1673-5374.208542 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Invited Review
Flores, Gonzalo
Curcuma longa L. extract improves the cortical neural connectivity during the aging process
title Curcuma longa L. extract improves the cortical neural connectivity during the aging process
title_full Curcuma longa L. extract improves the cortical neural connectivity during the aging process
title_fullStr Curcuma longa L. extract improves the cortical neural connectivity during the aging process
title_full_unstemmed Curcuma longa L. extract improves the cortical neural connectivity during the aging process
title_short Curcuma longa L. extract improves the cortical neural connectivity during the aging process
title_sort curcuma longa l. extract improves the cortical neural connectivity during the aging process
topic Invited Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514855/
https://www.ncbi.nlm.nih.gov/pubmed/28761413
http://dx.doi.org/10.4103/1673-5374.208542
work_keys_str_mv AT floresgonzalo curcumalongalextractimprovesthecorticalneuralconnectivityduringtheagingprocess