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Pannexin1 knockout and blockade reduces ischemic stroke injury in female, but not in male mice

The membrane channel Pannexin 1 (Panx1) mediates apoptotic and inflammatory signaling cascades in injured neurons, responses previously shown to be sexually dimorphic under ischemic conditions. We tested the hypothesis that Panx1 plays an underlying role in mediating sex differences in stroke outcom...

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Detalles Bibliográficos
Autores principales:	Freitas-Andrade, Moises, Bechberger, John F., MacVicar, Brian A., Viau, Victor, Naus, Christian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper: Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514885/ https://www.ncbi.nlm.nih.gov/pubmed/28445139 http://dx.doi.org/10.18632/oncotarget.16937

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