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Potential biomarkers of DNA replication stress in cancer

Oncogene activation is an established driver of tumorigenesis. An apparently inevitable consequence of oncogene activation is the generation of DNA replication stress (RS), a feature common to most cancer cells. RS, in turn, is a causal factor in the development of chromosome instability (CIN), a ne...

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Detalles Bibliográficos
Autores principales: Ren, Liqun, Chen, Long, Wu, Wei, Garribba, Lorenza, Tian, Huanna, Liu, Zihui, Vogel, Ivan, Li, Chunhui, Hickson, Ian D., Liu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514887/
https://www.ncbi.nlm.nih.gov/pubmed/28445142
http://dx.doi.org/10.18632/oncotarget.16940

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