Epigenetic up-regulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells

The alterations of ribosome biogenesis and protein synthesis play a direct role in the development of tumors. The accessibility and transcription of ribosomal genes is controlled at several levels, with their epigenetic regulation being one of the most important. Here we explored the JmjC domain-con...

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Detalles Bibliográficos
Autores principales: Galbiati, Alice, Penzo, Marianna, Bacalini, Maria Giulia, Onofrillo, Carmine, Guerrieri, Ania Naila, Garagnani, Paolo, Franceschi, Claudio, Treré, Davide, Montanaro, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514893/
https://www.ncbi.nlm.nih.gov/pubmed/28415746
http://dx.doi.org/10.18632/oncotarget.16181

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