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A novel triazolonaphthalimide induces apoptosis and inhibits tumor growth by targeting DNA and DNA-associated processes

DNA and DNA-associated processes have been classes of the most important targets of chemotherapeutic drugs. As classic DNA intercalators and topoisomerase inhibitors, naphthalimides have been extensively investigated as potential anti-cancer drugs. We recently synthesized a novel series of triazolon...

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Detalles Bibliográficos
Autores principales: Ji, Liyan, Yang, Simin, Li, Shasha, Liu, Shan, Tang, Shunan, Liu, Zhongqiu, Meng, Xiangbao, Yu, Siwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514917/
https://www.ncbi.nlm.nih.gov/pubmed/28445124
http://dx.doi.org/10.18632/oncotarget.16962

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