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Detection of a combination of serum IgG and IgA antibodies against selected mycobacterial targets provides promising diagnostic signatures for active TB

Immunoglobulin G (IgG) based tests for the diagnosis of active tuberculosis (TB) disease often show a lack of specificity in TB endemic regions, which is mainly due to a high background prevalence of LTBI. Here, we investigated the combined performance of the responses of different Ig classes to sel...

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Detalles Bibliográficos
Autores principales: Awoniyi, Dolapo O., Baumann, Ralf, Chegou, Novel N., Kriel, Belinda, Jacobs, Ruschca, Kidd, Martin, Loxton, Andre G., Kaempfer, Susanne, Singh, Mahavir, Walzl, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514927/
https://www.ncbi.nlm.nih.gov/pubmed/28415587
http://dx.doi.org/10.18632/oncotarget.16401