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Anti-tumor activity of an immunotoxin (TGFα-PE38) delivered by attenuated Salmonella typhimurium

The anticancer strategy underlying the use of immunotoxins is as follows: the cancer-binding domain delivers the toxin to a cancer cell, after which the toxin enters and kills the cell. TGFα-PE38 is an immunotoxin comprising transforming growth factor alpha (TGFα), a natural ligand of epidermal grow...

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Detalles Bibliográficos
Autores principales: Lim, Daejin, Kim, Kwang Soo, Kim, Hyunju, Ko, Kyong-Cheol, Song, Jae Jun, Choi, Jong Hyun, Shin, Minsang, Min, Jung-joon, Jeong, Jae-Ho, Choy, Hyon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514929/
https://www.ncbi.nlm.nih.gov/pubmed/28473665
http://dx.doi.org/10.18632/oncotarget.17197

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