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Anti-tumor activity of an immunotoxin (TGFα-PE38) delivered by attenuated Salmonella typhimurium
The anticancer strategy underlying the use of immunotoxins is as follows: the cancer-binding domain delivers the toxin to a cancer cell, after which the toxin enters and kills the cell. TGFα-PE38 is an immunotoxin comprising transforming growth factor alpha (TGFα), a natural ligand of epidermal grow...
Autores principales: | Lim, Daejin, Kim, Kwang Soo, Kim, Hyunju, Ko, Kyong-Cheol, Song, Jae Jun, Choi, Jong Hyun, Shin, Minsang, Min, Jung-joon, Jeong, Jae-Ho, Choy, Hyon E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514929/ https://www.ncbi.nlm.nih.gov/pubmed/28473665 http://dx.doi.org/10.18632/oncotarget.17197 |
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