Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1

Cohesin is a multi-protein complex that tethers sister chromatids during mitosis and mediates DNA repair, genome compartmentalisation and regulation of gene expression. Cohesin subunits frequently acquire cancer loss-of-function alterations and act as tumour suppressors in several tumour types. This...

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Detalles Bibliográficos
Autores principales: Benedetti, Lorena, Cereda, Matteo, Monteverde, LeeAnn, Desai, Nikita, Ciccarelli, Francesca D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514935/
https://www.ncbi.nlm.nih.gov/pubmed/28430577
http://dx.doi.org/10.18632/oncotarget.16838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514935/
https://www.ncbi.nlm.nih.gov/pubmed/28430577
http://dx.doi.org/10.18632/oncotarget.16838

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