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Stereochemical preference toward oncotarget: Design, synthesis and in vitro anticancer evaluation of diastereomeric β-lactams

PURPOSE: In the battle against cancer discovery of new and novel chemotherapeutic agent demands extreme obligation. Development of anticancer compounds with higher potency and reduced side-effects is timely and challenging. EXPERIMENTAL DESIGN: A small series of fourteen diastereomeric β-lactams (se...

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Detalles Bibliográficos
Autores principales: Olazarán-Santibáñez, Fabián, Bandyopadhyay, Debasish, Carranza-Rosales, Pilar, Rivera, Gildardo, Balderas-Rentería, Isaías
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514948/
https://www.ncbi.nlm.nih.gov/pubmed/28562328
http://dx.doi.org/10.18632/oncotarget.18077