Regulatory functional territory of PLK-1 and their substrates beyond mitosis

Polo-like kinase 1 (PLK-1) is a well-known (Ser/Thr) mitotic protein kinase and is considered as a proto-oncogene. As hyper-activation of PLK-1 is broadly associated with poor prognosis and cancer progression, it is one of the most extensively studied mitotic kinases. During mitosis, PLK-1 regulates...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Shiv, Sharma, Garima, Chakraborty, Chiranjib, Sharma, Ashish Ranjan, Kim, Jaebong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514964/
https://www.ncbi.nlm.nih.gov/pubmed/28415805
http://dx.doi.org/10.18632/oncotarget.16290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514964/
https://www.ncbi.nlm.nih.gov/pubmed/28415805
http://dx.doi.org/10.18632/oncotarget.16290

Ejemplares similares