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Role of EZH2 in cancer stem cells: from biological insight to a therapeutic target

Epigenetic modifications in cancer stem cells largely result in phenotypic and functional heterogeneity in many solid tumors. Increasing evidence indicates that enhancer of zeste homolog 2 (EZH2), the catalytic subunit of Polycomb repressor complex 2, is highly expressed in cancer stem cells of nume...

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Detalles Bibliográficos
Autores principales:	Wen, Yiping, Cai, Jing, Hou, Yaya, Huang, Zaiju, Wang, Zehua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514966/ https://www.ncbi.nlm.nih.gov/pubmed/28415635 http://dx.doi.org/10.18632/oncotarget.16467

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