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The oxidation state of the cytoplasmic glutathione redox system does not correlate with replicative lifespan in yeast

What is cause and what is consequence of aging and whether reactive oxygen species (ROS) contribute to this phenomenon is debated since more than 50 years. Notwithstanding, little is known about the cellular buffer and redox systems in aging Saccharomyces cerevisiae, which is a model for aging stem...

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Detalles Bibliográficos
Autores principales: Knieß, Robert A, Mayer, Matthias P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515007/
https://www.ncbi.nlm.nih.gov/pubmed/28721277
http://dx.doi.org/10.1038/npjamd.2016.28

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