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Cross-cultural assessment of HIV-associated cognitive impairment using the Kaufman assessment battery for children: a systematic review

Introduction: Despite improved efficacy of, and access to, combination antiretroviral therapy (cART), HIV-associated cognitive impairments remain prevalent in both children and adults. Neuropsychological tests that detect such impairment can help clinicians formulate effective treatment plans. The K...

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Autores principales: van Wyhe, Kaylee S, van de Water, Tanya, Boivin, Michael J, Cotton, Mark F, Thomas, Kevin GF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515037/
https://www.ncbi.nlm.nih.gov/pubmed/28664684
http://dx.doi.org/10.7448/IAS.20.1.21412
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author van Wyhe, Kaylee S
van de Water, Tanya
Boivin, Michael J
Cotton, Mark F
Thomas, Kevin GF
author_facet van Wyhe, Kaylee S
van de Water, Tanya
Boivin, Michael J
Cotton, Mark F
Thomas, Kevin GF
author_sort van Wyhe, Kaylee S
collection PubMed
description Introduction: Despite improved efficacy of, and access to, combination antiretroviral therapy (cART), HIV-associated cognitive impairments remain prevalent in both children and adults. Neuropsychological tests that detect such impairment can help clinicians formulate effective treatment plans. The Kaufman Assessment Battery for Children (KABC), although developed and standardized in the United States, is used frequently in many different countries and cultural contexts to assess paediatric performance across various cognitive domains. This systematic review investigated the cross-cultural utility of the original KABC, and its 2nd edition (KABC-II), in detecting HIV-associated cognitive impairment in children and adolescents. Methods: We entered relevant keywords and MeSH terms into the PubMed, PsycInfo, EBSCOHost, ProQuest, and Scopus databases, with search limits set from 1983–2017. Two independent reviewers evaluated the retrieved abstracts and manuscripts. Studies eligible for inclusion in the review were those that (a) used the KABC/KABC-II to assess cognitive function in children/adolescents aged 2–18 years, (b) featured a definition of cognitive impairment (e.g. >2 SD below the mean) or compared the performance of HIV-infected and uninfected control groups, and (c) used a sample excluded from population on which the instruments were normed. Results and discussion: We identified nine studies (eight conducted in African countries, and one in the United Kingdom) to comprise the review’s sample. All studies detected cognitive impairment in HIV-infected children, including those who were cART-naïve or who were cART treated and clinically stable. KABC/KABC-II subtests assessing simultaneous processing appeared most sensitive. Evaluation of the methodological quality of the selected studies by two independent reviews suggested that shortcomings included reporting and selection biases. Conclusions: This systematic review provides evidence for the cross-cultural utility of the KABC/KABC-II, particularly the simultaneous processing subtests, in detecting cognitive impairment in HIV-infected children (including those who are clinically stable). Although the current results suggest there is justification for using the KABC/KABC-II primarily in East Africa, further investigation is required to explore the instrument’s utility in other HIV-prevalent regions of the globe.
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spelling pubmed-55150372017-07-26 Cross-cultural assessment of HIV-associated cognitive impairment using the Kaufman assessment battery for children: a systematic review van Wyhe, Kaylee S van de Water, Tanya Boivin, Michael J Cotton, Mark F Thomas, Kevin GF J Int AIDS Soc Review Article Introduction: Despite improved efficacy of, and access to, combination antiretroviral therapy (cART), HIV-associated cognitive impairments remain prevalent in both children and adults. Neuropsychological tests that detect such impairment can help clinicians formulate effective treatment plans. The Kaufman Assessment Battery for Children (KABC), although developed and standardized in the United States, is used frequently in many different countries and cultural contexts to assess paediatric performance across various cognitive domains. This systematic review investigated the cross-cultural utility of the original KABC, and its 2nd edition (KABC-II), in detecting HIV-associated cognitive impairment in children and adolescents. Methods: We entered relevant keywords and MeSH terms into the PubMed, PsycInfo, EBSCOHost, ProQuest, and Scopus databases, with search limits set from 1983–2017. Two independent reviewers evaluated the retrieved abstracts and manuscripts. Studies eligible for inclusion in the review were those that (a) used the KABC/KABC-II to assess cognitive function in children/adolescents aged 2–18 years, (b) featured a definition of cognitive impairment (e.g. >2 SD below the mean) or compared the performance of HIV-infected and uninfected control groups, and (c) used a sample excluded from population on which the instruments were normed. Results and discussion: We identified nine studies (eight conducted in African countries, and one in the United Kingdom) to comprise the review’s sample. All studies detected cognitive impairment in HIV-infected children, including those who were cART-naïve or who were cART treated and clinically stable. KABC/KABC-II subtests assessing simultaneous processing appeared most sensitive. Evaluation of the methodological quality of the selected studies by two independent reviews suggested that shortcomings included reporting and selection biases. Conclusions: This systematic review provides evidence for the cross-cultural utility of the KABC/KABC-II, particularly the simultaneous processing subtests, in detecting cognitive impairment in HIV-infected children (including those who are clinically stable). Although the current results suggest there is justification for using the KABC/KABC-II primarily in East Africa, further investigation is required to explore the instrument’s utility in other HIV-prevalent regions of the globe. Taylor & Francis 2017-06-14 /pmc/articles/PMC5515037/ /pubmed/28664684 http://dx.doi.org/10.7448/IAS.20.1.21412 Text en © 2017 Van Wyhe KS et al; licensee International AIDS Society. http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
van Wyhe, Kaylee S
van de Water, Tanya
Boivin, Michael J
Cotton, Mark F
Thomas, Kevin GF
Cross-cultural assessment of HIV-associated cognitive impairment using the Kaufman assessment battery for children: a systematic review
title Cross-cultural assessment of HIV-associated cognitive impairment using the Kaufman assessment battery for children: a systematic review
title_full Cross-cultural assessment of HIV-associated cognitive impairment using the Kaufman assessment battery for children: a systematic review
title_fullStr Cross-cultural assessment of HIV-associated cognitive impairment using the Kaufman assessment battery for children: a systematic review
title_full_unstemmed Cross-cultural assessment of HIV-associated cognitive impairment using the Kaufman assessment battery for children: a systematic review
title_short Cross-cultural assessment of HIV-associated cognitive impairment using the Kaufman assessment battery for children: a systematic review
title_sort cross-cultural assessment of hiv-associated cognitive impairment using the kaufman assessment battery for children: a systematic review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515037/
https://www.ncbi.nlm.nih.gov/pubmed/28664684
http://dx.doi.org/10.7448/IAS.20.1.21412
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