Preventing breast cancer now by acting on what we already know

The age-specific rate of breast cancer rises rapidly through premenopausal years and significantly more slowly after menopause. Reproductive factors affect cell proliferation and the accumulation of genetic changes. Lifetime risk of breast cancer is linearly related to the length of the interval fro...

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Detalles Bibliográficos
Autores principales: Colditz, Graham A, Bohlke, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515195/
https://www.ncbi.nlm.nih.gov/pubmed/28721366
http://dx.doi.org/10.1038/npjbcancer.2015.9
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author Colditz, Graham A
Bohlke, Kari
author_facet Colditz, Graham A
Bohlke, Kari
author_sort Colditz, Graham A
collection PubMed
description The age-specific rate of breast cancer rises rapidly through premenopausal years and significantly more slowly after menopause. Reproductive factors affect cell proliferation and the accumulation of genetic changes. Lifetime risk of breast cancer is linearly related to the length of the interval from menarche to first birth. Lifestyle changes that accompany industrialization, together with shifting reproductive patterns, drive up incidence rates. Prevention must begin early in the life as almost one-quarter of cases are diagnosed before age 50 in high-income countries. This requires greater emphasis on prevention across the life course to address the global burden of breast cancer.
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spelling pubmed-55151952017-07-18 Preventing breast cancer now by acting on what we already know Colditz, Graham A Bohlke, Kari NPJ Breast Cancer Perspective The age-specific rate of breast cancer rises rapidly through premenopausal years and significantly more slowly after menopause. Reproductive factors affect cell proliferation and the accumulation of genetic changes. Lifetime risk of breast cancer is linearly related to the length of the interval from menarche to first birth. Lifestyle changes that accompany industrialization, together with shifting reproductive patterns, drive up incidence rates. Prevention must begin early in the life as almost one-quarter of cases are diagnosed before age 50 in high-income countries. This requires greater emphasis on prevention across the life course to address the global burden of breast cancer. Nature Publishing Group 2015-07-22 /pmc/articles/PMC5515195/ /pubmed/28721366 http://dx.doi.org/10.1038/npjbcancer.2015.9 Text en Copyright © 2015 Breast Cancer Research Foundation/Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Perspective
Colditz, Graham A
Bohlke, Kari
Preventing breast cancer now by acting on what we already know
title Preventing breast cancer now by acting on what we already know
title_full Preventing breast cancer now by acting on what we already know
title_fullStr Preventing breast cancer now by acting on what we already know
title_full_unstemmed Preventing breast cancer now by acting on what we already know
title_short Preventing breast cancer now by acting on what we already know
title_sort preventing breast cancer now by acting on what we already know
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515195/
https://www.ncbi.nlm.nih.gov/pubmed/28721366
http://dx.doi.org/10.1038/npjbcancer.2015.9
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