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Spatiotemporal progression of metastatic breast cancer: a Markov chain model highlighting the role of early metastatic sites
BACKGROUND: Cancer cell migration patterns are critical for understanding metastases and clinical evolution. Breast cancer spreads from one organ system to another via hematogenous and lymphatic routes. Although patterns of spread may superficially seem random and unpredictable, we explored the poss...
Autores principales: | Newton, Paul K, Mason, Jeremy, Venkatappa, Neethi, Jochelson, Maxine S, Hurt, Brian, Nieva, Jorge, Comen, Elizabeth, Norton, Larry, Kuhn, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515198/ https://www.ncbi.nlm.nih.gov/pubmed/28721371 http://dx.doi.org/10.1038/npjbcancer.2015.18 |
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