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A search for synergy in the binding kinetics of Trastuzumab and Pertuzumab whole and F(ab) to Her2
Therapeutic efficacy resulting from combining Trastuzumab and Pertuzumab in the treatment of Her2 overexpressing breast cancer patients has been shown to increase patient survival. This is thought to arise from inhibition of receptor dimerization and the immune tagging of the cancer cells; however,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515203/ https://www.ncbi.nlm.nih.gov/pubmed/28721368 http://dx.doi.org/10.1038/npjbcancer.2015.12 |