Dishevelled and Wnt signaling: is the nucleus the final frontier?

The phosphoprotein Dishevelled (Dsh) is an essential component of Wnt signaling pathways and transduces signals into three separate branches, the canonical, non-canonical and Ca(2+ )pathways. How Dsh focuses signaling into these branches remains mysterious, but a new study reveals the importance of...

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Detalles Bibliográficos
Autores principales: Habas, Raymond, Dawid, Igor B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC551522/
https://www.ncbi.nlm.nih.gov/pubmed/15720723
http://dx.doi.org/10.1186/jbiol22
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author Habas, Raymond
Dawid, Igor B
author_facet Habas, Raymond
Dawid, Igor B
author_sort Habas, Raymond
collection PubMed
description The phosphoprotein Dishevelled (Dsh) is an essential component of Wnt signaling pathways and transduces signals into three separate branches, the canonical, non-canonical and Ca(2+ )pathways. How Dsh focuses signaling into these branches remains mysterious, but a new study reveals the importance of nuclear localization of Dsh for pathway-specific activation.
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spelling pubmed-5515222005-03-03 Dishevelled and Wnt signaling: is the nucleus the final frontier? Habas, Raymond Dawid, Igor B J Biol Minireview The phosphoprotein Dishevelled (Dsh) is an essential component of Wnt signaling pathways and transduces signals into three separate branches, the canonical, non-canonical and Ca(2+ )pathways. How Dsh focuses signaling into these branches remains mysterious, but a new study reveals the importance of nuclear localization of Dsh for pathway-specific activation. BioMed Central 2005 2005-02-17 /pmc/articles/PMC551522/ /pubmed/15720723 http://dx.doi.org/10.1186/jbiol22 Text en Copyright © 2005 BioMed Central Ltd
spellingShingle Minireview
Habas, Raymond
Dawid, Igor B
Dishevelled and Wnt signaling: is the nucleus the final frontier?
title Dishevelled and Wnt signaling: is the nucleus the final frontier?
title_full Dishevelled and Wnt signaling: is the nucleus the final frontier?
title_fullStr Dishevelled and Wnt signaling: is the nucleus the final frontier?
title_full_unstemmed Dishevelled and Wnt signaling: is the nucleus the final frontier?
title_short Dishevelled and Wnt signaling: is the nucleus the final frontier?
title_sort dishevelled and wnt signaling: is the nucleus the final frontier?
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC551522/
https://www.ncbi.nlm.nih.gov/pubmed/15720723
http://dx.doi.org/10.1186/jbiol22
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AT dawidigorb dishevelledandwntsignalingisthenucleusthefinalfrontier

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