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Massively parallel sequencing analysis of synchronous fibroepithelial lesions supports the concept of progression from fibroadenoma to phyllodes tumor

Phyllodes tumors (PTs) and fibroadenomas (FAs) are fibroepithelial lesions (FELs) of the breast. Although mutations affecting exon 2 of MED12 are highly recurrent in FAs and PTs, TERT promoter hotspot mutations are frequently found in PTs but are vanishingly rare in FAs. Malignant transformation of...

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Detalles Bibliográficos
Autores principales:	Piscuoglio, Salvatore, Geyer, Felipe C, Burke, Kathleen A, Murray, Melissa P, Ng, Charlotte KY, Mota, Alba, Marchio, Caterina, Berman, Samuel H, Norton, Larry, Brogi, Edi, Weigelt, Britta, Reis-Filho, Jorge S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515337/ https://www.ncbi.nlm.nih.gov/pubmed/28721388 http://dx.doi.org/10.1038/npjbcancer.2016.35

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