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TNF is a key cytokine mediating neutrophil cytotoxic activity in breast cancer patients

We have previously shown a novel antimetastatic role for neutrophils in the premetastatic lung of mice in models of breast cancer. Here we expand on those findings in the context of human breast cancer. We assessed the cytotoxicity of neutrophils from 90 newly diagnosed breast cancer patients, 24 du...

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Detalles Bibliográficos
Autores principales: Comen, Elizabeth, Wojnarowicz, Paulina, Seshan, Venkatraman E, Shah, Riddhi, Coker, Courtney, Norton, Larry, Benezra, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515342/
https://www.ncbi.nlm.nih.gov/pubmed/28721376
http://dx.doi.org/10.1038/npjbcancer.2016.9