Frizzled 7 and PIP(2) binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling

PDZ domain-containing proteins work as intracellular scaffolds to control spatio-temporal aspects of cell signalling. This function is supported by the ability of their PDZ domains to bind other proteins such as receptors, but also phosphoinositide lipids important for membrane trafficking. Here we...

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Detalles Bibliográficos
Autores principales: Egea-Jimenez, Antonio Luis, Gallardo, Rodrigo, Garcia-Pino, Abel, Ivarsson, Ylva, Wawrzyniak, Anna Maria, Kashyap, Rudra, Loris, Remy, Schymkowitz, Joost, Rousseau, Frederic, Zimmermann, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515355/
https://www.ncbi.nlm.nih.gov/pubmed/27386966
http://dx.doi.org/10.1038/ncomms12101

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